abstract：BACKGROUND:Academic medical centers are faced with increasing volumes, higher acuity, and, as a consequence, capacity issues. These affect operating room (OR) use and patient throughput, with negative impact on finances and patient and physician satisfaction. We evaluated our experiences in dealing with OR efficiency a...

journal_title：Journal of the American College of Surgeons

authors： McGowan JE,Truwit JD,Cipriano P,Howell RE,VanBree M,Garson A Jr,Hanks JB

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Pancreaticoduodenectomy (PD) is a complex general surgical procedure originally associated with significant perioperative morbidity and mortality. Multiple studies have now shown that this operation can be performed quite safely at high-volume institutions that develop a particular expertise. Critical pathwa...

journal_title：Journal of the American College of Surgeons

authors： Kennedy EP,Rosato EL,Sauter PK,Rosenberg LM,Doria C,Marino IR,Chojnacki KA,Berger AC,Yeo CJ

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The role of C-Jun N-terminal Kinase (c-Jun Kinase) in apoptosis is unclear. It is likely that c-Jun Kinase activation is cell type and stimulus dependent. c-Jun Kinase promotes tumor necrosis factor (TNF)-alpha mediated apoptosis in nuclear factor (NF)-KB deficient cells. Minimal NF-KB expression may be enou...

journal_title：Journal of the American College of Surgeons

authors： Rushing GD,Britt LD

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Significant confusion exists about management of blunt carotid injuries (BCI). Currently, three common treatments are being used without significant longterm followup data to demonstrate efficacy. Although heparin has been shown to reduce in-hospital stroke rates, antiplatelet therapy (aspirin and clopidogre...

journal_title：Journal of the American College of Surgeons

authors： Edwards NM,Fabian TC,Claridge JA,Timmons SD,Fischer PE,Croce MA

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The influence of increased body mass index (BMI) on morbidity and mortality in critically injured trauma patients has been studied, with conflicting results. The objective of this study was to investigate the relationship between stratified BMI and outcomes in blunt injured patients. STUDY DESIGN:Consecutiv...

journal_title：Journal of the American College of Surgeons

authors： Newell MA,Bard MR,Goettler CE,Toschlog EA,Schenarts PJ,Sagraves SG,Holbert D,Pories WJ,Rotondo MF

更新日期：2007-05-01 00:00:00

abstract：UNLABELLED:Some of the concepts contained here have been discussed and incorporated in another publication, but the data are entirely unique to this manuscript. (See: Transforming the Surgical "Time-Out" Into a Comprehensive "Preparatory Pause." Backster A, Teo A, Swift M, MD, Polk HC Jr, MD, FACS, Harken AH, MD, FACS....

journal_title：Journal of the American College of Surgeons

authors： Altpeter T,Luckhardt K,Lewis JN,Harken AH,Polk HC Jr

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Postoperative ileus (POI), an interruption of coordinated bowel motility after operation, is exacerbated by opioids used to manage pain. Alvimopan, a peripherally acting mu-opioid receptor antagonist, accelerated gastrointestinal (GI) recovery after bowel resection in randomized, double-blind, placebo-contro...

journal_title：Journal of the American College of Surgeons

authors： Wolff BG,Weese JL,Ludwig KA,Delaney CP,Stamos MJ,Michelassi F,Du W,Techner L

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Although established for metastatic colorectal (CR) and neuroendocrine (NE) malignancies, the role of partial hepatectomy in management of metastases from other primaries (NCRNE) is not well-defined. STUDY DESIGN:The objective of this retrospective study is to compare outcomes after partial hepatectomy for ...

journal_title：Journal of the American College of Surgeons

authors： Reddy SK,Barbas AS,Marroquin CE,Morse MA,Kuo PC,Clary BM

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:There are few reproducible models of blast injury, so it is difficult to evaluate new or existing therapies. We developed a clinically relevant polytrauma model to test the hypothesis that cerebrovascular resuscitation is optimized when intravenous fluid is restricted. STUDY DESIGN:Anesthetized swine (42+/-...

journal_title：Journal of the American College of Surgeons

authors： Earle SA,de Moya MA,Zuccarelli JE,Norenberg MD,Proctor KG

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Pediatric appendicitis is treated by both pediatric and general surgeons. We investigated whether specialty-dependent differences existed in patients' characteristics and outcomes. STUDY DESIGN:A retrospective chart review of 465 consecutive children treated for appendicitis at a university-affiliated child...

journal_title：Journal of the American College of Surgeons

authors： Emil SG,Taylor MB

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:A low prevalence of high-level clinical studies in the surgical literature has been reported previously. We reviewed a recent sample of surgical publications to assess the current status of clinical research. STUDY DESIGN:A 3-month sample of journal articles in Archives of Surgery, Surgery, and Annals of Su...

journal_title：Journal of the American College of Surgeons

authors： Chang DC,Matsen SL,Simpkins CE

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Cirrhosis as an independent predictor of poor outcomes in trauma patients was identified in 1990. We hypothesized that the degree of preinjury hepatic dysfunction is, by itself, an independent predictor of mortality. STUDY DESIGN:The trauma registry at our Level I trauma center was queried for all ICD-9 cod...

journal_title：Journal of the American College of Surgeons

authors： Dangleben DA,Jazaeri O,Wasser T,Cipolle M,Pasquale M

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Falls from a height are a major cause of morbidity and hospital cost. Spinal injury is frequently associated with falls from height, but reliable predictive factors have not been identified. Diagnostic evaluation of the spine is complex and debated. Our objective was to characterize spinal injury after falls...

journal_title：Journal of the American College of Surgeons

authors： Velmahos GC,Spaniolas K,Alam HB,de Moya M,Gervasini A,Petrovick L,Conn AK

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The technique of total mesorectal excision (TME) increases the risk of anastomotic leakage. The impact of postoperative morbidity of TME on longterm survival has never been described. We retrospectively analyzed factors that might influence survival after TME for rectal cancer, including postoperative morbid...

journal_title：Journal of the American College of Surgeons

authors： Laurent C,Nobili S,Rullier A,Vendrely V,Saric J,Rullier E

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Male breast cancer accounts for < 1% of breast cancers. Sentinel lymph node (SLN) operation is commonly used in the evaluation of female breast cancer patients. The purpose of this study was to determine whether SLN operation is as feasible and accurate in male patients compared with female patients. STUDY ...

journal_title：Journal of the American College of Surgeons

authors： Boughey JC,Bedrosian I,Meric-Bernstam F,Ross MI,Kuerer HM,Akins JS,Giordano SH,Babiera GV,Ames FC,Hunt KK

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Acinetobacter calcoaceticus-baumannii complex (Acb) is recognized as an important cause of nosocomial infections. Although Acb can be associated with multidrug resistance, its impact on mortality in burn patients has not been fully elucidated. STUDY DESIGN:In a retrospective cohort study assessing medical r...

journal_title：Journal of the American College of Surgeons

authors： Albrecht MC,Griffith ME,Murray CK,Chung KK,Horvath EE,Ward JA,Hospenthal DR,Holcomb JB,Wolf SE

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:This study describes, quantifies, and evaluates the University of Michigan Department of Surgery medical malpractice experience for the 1992 to 2002 period. The goal is to gain an understanding of what our claims experience has been, what services are highest risk, and where the financial exposure lies. STU...

journal_title：Journal of the American College of Surgeons

authors： Taheri PA,Butz DA,Anderson S,Boothman R,Blanco OL,Greenfield LJ,Mulholland MM

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Identification of correlates of contemporary US medical graduates' surgical career plans can provide insights about the emerging surgical workforce composition and inform future recruitment efforts. STUDY DESIGN:We analyzed individualized records of 95,176 graduates who completed the 1997 to 2004 Associatio...

journal_title：Journal of the American College of Surgeons

authors： Andriole DA,Klingensmith ME,Jeffe DB

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Most studies comparing surgical results of laparoscopic procedures for gastric cancer with open gastrectomies have been conducted based on limited experience. We aimed to compare laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) after a protracted learning experien...

journal_title：Journal of the American College of Surgeons

authors： Lee SI,Choi YS,Park DJ,Kim HH,Yang HK,Kim MC

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:After excision of an abnormal gland, the dynamics of intraoperative parathyroid hormone (PTH) levels signal whether or not more hypersecreting tissue is present. This quantitative assurance of operative success has led to targeted exploration of the hyperfunctioning gland(s). Some have questioned the need fo...

journal_title：Journal of the American College of Surgeons

authors： Carneiro-Pla DM,Solorzano CC,Irvin GL 3rd

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Accurate detection of metastasis to lymph nodes is an essential component of the approach to treatment. The purpose of this study was to evaluate the utility of magnetic resonance imaging with ferumoxtran-10 in diagnosing lymph node metastasis in esophageal cancer. STUDY DESIGN:Sixteen patients with esophag...

journal_title：Journal of the American College of Surgeons

authors： Nishimura H,Tanigawa N,Hiramatsu M,Tatsumi Y,Matsuki M,Narabayashi I

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Effective use of ultrasonography (US) by surgeons was demonstrated a decade ago. Major surgical organizations now require its incorporation into surgical training and practice. But little information about the teaching of US to surgical residents exists. This study assesses the current status of US training ...

journal_title：Journal of the American College of Surgeons

authors： Freitas ML,Frangos SG,Frankel HL

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Several surgical treatment options for morbid obesity exist. Currently, there are no studies that objectively compare complication rates after laparoscopic bariatric operations performed at a single institution. We objectively classify and compare complications resulting from laparoscopic adjustable gastric ...

journal_title：Journal of the American College of Surgeons

authors： Parikh MS,Laker S,Weiner M,Hajiseyedjavadi O,Ren CJ

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine postoperative outcomes and risk factors for morbidity and mortality in patients requiring surgery for bleeding peptic ulcer disease (PUD). Vagotomy and drainage procedures are technically simpler but are usually associated with higher ulcer recurrence rates. In cont...

journal_title：Journal of the American College of Surgeons

authors： de la Fuente SG,Khuri SF,Schifftner T,Henderson WG,Mantyh CR,Pappas TN

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Although the expanding and aging population will likely increase demand for surgical services, surgeons and other providers must develop strategies to optimize care. We sought to develop process-based quality indicators for elderly patients undergoing abdominal operations to identify necessary and meaningful...

journal_title：Journal of the American College of Surgeons

authors： McGory ML,Shekelle PG,Rubenstein LZ,Fink A,Ko CY

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine how often patients with ductal carcinoma in situ and T1a/b N0 cancer are offered and accept tamoxifen for secondary chemoprevention. STUDY DESIGN:A retrospective review of 284 patients with T1a/b N0 invasive cancer treated between February 1995 and December 2001 an...

journal_title：Journal of the American College of Surgeons

authors： Nakhlis F,Lazarus L,Hou N,Acharya S,Khan SA,Staradub VL,Rademaker AW,Morrow M

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:While specialty-level evaluations evolve from traditional examinations to objective structured clinical examination-like assessments, a broader range of competencies are tested; consequently, examiners are forced to integrate results when making a determination of competency. The aim of this study was to des...

journal_title：Journal of the American College of Surgeons

authors： Sidhu RS,McIlroy JH,Regehr G

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine 1,014 consecutive laparoscopic adjustable gastric banding (LAGB) procedures with up to 48 months of followup, including evolution and changes in surgical technique, learning curve issues, weight loss outcomes, and complications. STUDY DESIGN:Between October 2000 and ...

journal_title：Journal of the American College of Surgeons

authors： Ponce J,Paynter S,Fromm R

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Thyroid surgery is performed using general anesthesia by the majority of surgeons in current practice. This study was conducted to analyze the utility and safety of local anesthesia for thyroid surgery. STUDY DESIGN:Prospective data were collected for 1,025 consecutive patients undergoing thyroidectomy usin...

journal_title：Journal of the American College of Surgeons

authors： Spanknebel K,Chabot JA,DiGiorgi M,Cheung K,Lee S,Allendorf J,Logerfo P

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The number of patients requiring hemodialysis increases each year, with a large cohort of patients still requiring prosthetic grafts for hemodialysis. All available prosthetic vascular access grafts have predictable failure rates, leading to a large group of patients with multiple failed access grafts. This ...

journal_title：Journal of the American College of Surgeons

authors： Katzman HE,Glickman MH,Schild AF,Fujitani RM,Lawson JH

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to develop a performance-based laparoscopic suturing curriculum using simulators and to test the effectiveness (transferability) of the curriculum. STUDY DESIGN:Surgical residents (PGY1 to PGY5, n = 17) proficient in basic skills, but with minimal laparoscopic suturing experien...

journal_title：Journal of the American College of Surgeons

authors： Korndorffer JR Jr,Dunne JB,Sierra R,Stefanidis D,Touchard CL,Scott DJ

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Our goal was to identify factors that can be targeted during medical education to encourage a career in surgery. STUDY DESIGN:We conducted a cross-sectional survey of first and fourth year classes in a Liaison Committee on Medical Education-accredited medical school. Students scored 19 items about perceptio...

journal_title：Journal of the American College of Surgeons

authors： Brundage SI,Lucci A,Miller CC,Azizzadeh A,Spain DA,Kozar RA

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Expression of estrogen receptor-alpha (ERalpha) as determined by immunohistochemistry of tumor tissue is currently the most clinically useful test to predict hormone responsiveness of breast cancer. Thirty percent of ERalpha-positive breast cancers do not respond to hormonal therapy. GATA-3 is a transcriptio...

journal_title：Journal of the American College of Surgeons

authors： Parikh P,Palazzo JP,Rose LJ,Daskalakis C,Weigel RJ

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Afterbirth or placenta is normally discarded. But placental cord blood, because of its rich mix of fetal and adult hemoglobin, plasma, and high platelet count has the potential to be a safe alternative to adult blood. STUDY DESIGN:We transfused 413 U (range 50 mL to 146 mL; mean 86 mL+/-7.6 mL SD; median 80...

journal_title：Journal of the American College of Surgeons

authors： Bhattacharya N

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Although trauma patients often suffer direct lung damage, an equally destructive mechanism of lung injury involves postinjury systemic inflammation. We postulate that secretory phospholipase A(2) (sPLA(2)) release induced by trauma relates to systemic inflammation that compromises both lung function and clin...

journal_title：Journal of the American College of Surgeons

authors： Neidlinger NA,Hirvela ER,Skinner RA,Larkin SK,Harken AH,Kuypers FA

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Trauma is the number one cause of maternal death during pregnancy, but incidence of fetal loss exceeds maternal loss by more than 3 to 1. We hypothesized that we could identify women at risk for injury during pregnancy and focus our prevention efforts. STUDY DESIGN:Women of childbearing age in the American ...

journal_title：Journal of the American College of Surgeons

authors： Ikossi DG,Lazar AA,Morabito D,Fildes J,Knudson MM

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The destructive human consequences of terrorist bombing always challenge the medical system in diagnosis, decision making, and patient management. This injury is produced by multiple injury mechanisms, and departs from the conventional description of trauma complexity. Our objective was to characterize and c...

journal_title：Journal of the American College of Surgeons

authors： Kluger Y,Peleg K,Daniel-Aharonson L,Mayo A,Israeli Trauma Group.

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:To evaluate whether abdominal aortic aneurysm (AAA) growth in individual patients can be characterized as continuous or discontinuous (staccato). STUDY DESIGN:From 1996 to 2002, 609 patients presented with unruptured AAAs. Of these, 278 underwent prompt repair and 331 were observed. In this study, we includ...

journal_title：Journal of the American College of Surgeons

authors： Kurvers H,Veith FJ,Lipsitz EC,Ohki T,Gargiulo NJ,Cayne NS,Suggs WD,Timaran CH,Kwon GY,Rhee SJ,Santiago C

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Studies have shown that racial and socioeconomic differences lead to inequality in access to health care. It is unknown whether insurance status and race affect the choice of surgical treatment for patients presenting with appendicitis. STUDY DESIGN:Patients with primary ICD-9 procedure codes for laparoscop...

journal_title：Journal of the American College of Surgeons

authors： Guller U,Jain N,Curtis LH,Oertli D,Heberer M,Pietrobon R

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Fibulin-5 is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Because fibulin-5 expression is induced dramatically in endot...

journal_title：Journal of the American College of Surgeons

authors： Lee MJ,Roy NK,Mogford JE,Schiemann WP,Mustoe TA

更新日期：2004-09-01 00:00:00